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    | Condition | FDA‑approved drugs | Key points |
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    | **Male hypogonadism** – clinically documented deficiency of testosterone
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    | **Female hypogonadism** – low ovarian estrogen/testicular androgen leading to amenorrhea or menopause‑related symptoms | **Estradiol valerate**, **estriol**, **progesterone** (in combination for cycle regulation) | Requires evaluation of follicle‑stimulating hormone, estradiol, and other hormones. |
    | **Androgen deficiency in transgender women** – low testosterone levels | **Nandrolone decanoate** | Usually combined with estrogen therapy; monitoring required. |

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    Introduction to the R Programming Language





    Introduction to the R Programming Language


    The R programming language is an open-source, high-level
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    Key Features




    Statistical & graphical capabilities: R offers an extensive library
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    ---

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    #### Install R
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    # Create and manipulate data
    df %
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    print(df)
    ```

    #### Reading Data from a CSV
    ```r
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    ---

    ## 4. Practical Tips & Common Pitfalls

    | Situation | Tip / Avoidance |
    |-----------|-----------------|
    | **Large datasets** | Use `vroom::vroom()` or `data.table::fread()` for faster import; read only needed columns (`col_select`) |
    | **Mixed data types in a column** | Convert to character first, then to factor/ordered as appropriate |
    | **Unwanted leading/trailing whitespace** | Trim strings with `stringr::str_trim()` before converting |
    | **Missing values represented differently** | Specify `na.strings` (e.g., `"NA"`, `"n/a"`) during import |
    | **Non-ASCII characters** | Ensure UTF‑8 encoding; use `iconv()` if needed |

    ---

    ## 5. Summary Checklist

    | Step | Action | Tool / Function |
    |------|--------|-----------------|
    | Import data | Read CSV/Excel | `read.csv()`, `readxl::read_excel()` |
    | Inspect structure | View columns, dtypes | `str(df)`, `summary(df)` |
    | Convert factor → numeric | Use mapping table or `as.numeric(levels(...))...` | |
    | Validate conversion | Compare before/after | `all.equal()` |
    | Document mapping | Store mapping table for reproducibility | Data frame, write to CSV |

    By following this guide, you ensure that categorical codes in your dataset are accurately transformed into meaningful numeric values, facilitating robust analysis and interpretation.

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